The shooting happened around 7:15 p.m. Sunday night in the 8600 block of Calmont Avenue near Las Vegas Trail.
Officers say three people were hit by the gunfire. One was taken to Harris Methodist Hospital while the other two were taken to John Peter Smith Hospital.
Investigators are not sure what sparked the shooting, but say they are looking for two people who left the scene.
The three people who were taken to the hospital are said to have non-life threatening injuries.